Dr. Domenico Pratico, MD, FCPP | Temple University

Domenico Pratico, MD, FCPP, is a Professor of Neural Sciences at the Lewis Katz School of Medicine, Temple University, where he is also the Scott Richards North Star Charitable Foundation Chair in Alzheimer’s research.

His early work includes the development of analytic methods to measure oxidative stress, which was instrumental for the first demonstration that brain oxidative stress is an early event in AD. His lab has been on the forefront in the effort to unravel the mechanisms responsible for the effect that dietary lifestyle has on brain health and aging. His group was one of the first to demonstrate that intracellular endo-lysosomal transport system is essential for neuronal homeostasis and that it can be a therapeutic target against neurodegeneration.

His area of research is clinical pharmacology focusing on cellular and molecular mechanisms involved in brain health, brain aging and the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease and Frontotemporal dementia.

Dr. Praticò is the author of more than 320 original articles and 25 chapters in thematic books. During his career, he has received several awards for his accomplishments including the Zenith Award from the Alzheimer’s Association, Dorothy Dillon Eweson from the American Federation for Aging Research, the Paul W. Eberman Research Award and The Marconi Science Award.